Allowing Chinese-made vaccines in S'pore without rigid testing a step back against COVID efforts

Jun 12, 2021 | 🚀 Fathership AI

In a move aimed at having more people here to be vaccinated, the Ministry of Health (MOH) will allow access to other Covid-19 vaccines under the Pandemic Special Access Route (PSAR) - a process that provides time-limited approval for the use of unregistered vaccines under special circumstances.

These vaccines include the ones from Johnson & Johnson, Oxford-AstraZeneca, and Chinese-made vaccines Sinovac and Sinopharm.

Both Sinovac and Sinopharm use inactivated coronaviruses (weakened or dead viruses that are no longer infectious) to trigger an immune response in the body - a traditional approach to vaccine development. They have been shown in studies to be less effective than the vaccines developed by the pharmaceutical companies Pfizer and Moderna.

Pfizer and Moderna use a newer technology called Messenger RNA (mRNA). This modern approach teaches our immune system to cultivate a form of protein that can produce antibodies - which is what protects us against coronavirus.

The two vaccines currently used in Singapore's national vaccination programme - Pfizer-BioNTech and Moderna - are based on mRNA technology. Both were recommended by the expert committee and authorised by the Health Science Authority (HSA) under the PSAR.

The World Health Organization (WHO) granted emergency approval for the Sinopharm and Sinovac vaccine. This decision came despite WHO experts saying earlier that more data was needed.

Coronavirus cases surge in countries relying on Sinopharm and Sinovac vaccines

The spread of the virus has raised fresh questions about the effectiveness of China’s vaccines, particularly against variants.

While many countries, including the US, Israel and many in Europe, have been able to cut back on strict anti-coronavirus measures due to successful vaccination campaigns using Pfizer and Moderna jabs, other countries, including Bahrain and the United Arab Emirates, that have depended on China’s Sinopharm vaccine are suffering from a sharp rise in new infections.

Seychelles - the world's most vaccinated country - last month and now Mongolia in the past three weeks have both had large numbers of infections despite high vaccination rates. Both have used the Sinopharm vaccine from China, although Seychelles also relied partly on AstraZeneca vaccines.

Chile and Uruguay also saw Covid surge despite a high vaccination success. More than 93% of the doses administered in Chile so far have been Sinovac.

Confidence in the Chinese vaccine has fallen to the lowest level in Bahrain and the UAE. Bahrainis have taken to calling it “Marqdoush,” a traditional drink that was previously believed to cure several diseases but was later found to be ineffective. In the UAE, it is mockingly said of some who received the Sinopharm vaccine that they took a dose of “water and salt.”

Data transparency on Sinopharm and Sinovac efficacy rate

Data on the efficacy of both Sinopharm and Sinovac vaccines are varied.

Brazilian trials suggested an efficacy rate of around 50.4% for Sinovac but results from late-stage trials in Indonesia and Turkey suggested a much higher rate - between 65% and 83%.

The peer-reviewed study from Sinopharm’s Phase 3 trial, published at the end of May, found the vaccine to 79% effective at preventing symptomatic disease, but noted the predominantly young, healthy and male trial participants meant it had “insufficient power to test the efficacy among those with chronic diseases, women, (and) older adults,” a concern the WHO echoed for older people.

The study’s authors also noted that no conclusions could be drawn from the trial about the prevention of both severe and asymptomatic disease.

Unpublished data out of Serbia suggested that some people given the Sinopharm vaccine may not produce antibodies to fight off the pandemic coronavirus three months after vaccination, according to reporting by the Wall Street Journal.

“The Sinopharm vaccine is not immunogenic enough, and it appears that its impact is especially low on elderly recipients,” said Olgica Djurkovic-Djakovic, of the University of Belgrade, who led the unpublished study and shared the findings with the Journal.

In April, the head of China’s Centers for Disease Control and Prevention, George Gao, seemed to acknowledge this potential problem. “The efficacy of the existing vaccines is not high,” he said at a conference, discussing the country’s vaccines. Last month, Beijing reportedly began planning to offer third doses of the country’s vaccines to try to boost protection.

Sinopharm rarely addresses public concerns over efficacy. Chinese officials contend the line of questioning to be an example of anti-China bias and selective reporting ignoring deficiencies in other vaccines. Chinese Foreign Ministry spokesperson Hua Chunying said a Wall Street Journal article on the Seychelles “exposes their unhealthy mind-set of denigrating China at every turn.”

Pfizer and Moderna vaccines still more effective

Both the Pfizer-BioNTech and Moderna vaccines have shown to be highly efficacious, especially in protecting against severe COVID-19 disease and hospitalisation, said Singapore's expert committee and HSA.

It said the high efficacy of the vaccines was demonstrated in Phase 3 clinical trials, and further supported with data from real-world rollouts of the vaccines, including in the United States, the UK and Israel.

This also includes protection against key COVID-19 variants such as the Alpha and Beta variants, which were the predominant strains circulating in these countries. The Alpha variant, B117, was first detected in the UK while the Beta variant, B1351, was first detected in South Africa.

"In sum, the PSAR-authorised mRNA vaccines have reliable scientific evidence that they are safe and effective, and the (committee) continues to strongly recommend that medically eligible persons should be vaccinated with them," it said.

Singapore residents opting for alternative vaccines may be inoculated with a false sense of security

According to an interview with The New Paper last week (Jun 2), housewife Madam Doris Teo, 72, is relieved and eager for a shot at an alternative vaccine like Sinopharm or Sinovac.

Madam Teo could not receive either the Pfizer-BioNTech or Moderna vaccines due to her history of anaphylaxis - an allergic reaction. She said: "I will get the alternative vaccine because I would rather be vaccinated than not at all."

Unfortunately for Madam Teo, both Sinopharm and the Sinovac vaccine are not recommended for those with a history of anaphylaxis, at least according to WHO.

For Madam Teo and more than 30,000 individuals like her here, getting an alternative vaccine other than the authorised ones may give them a false sense of security and may risk further problems down the road such as having to get multiple booster shots.

UAE and Bahrain which has been administering Sinopharm booster shots since March, has reportedly undertaken a clandestine effort to revaccinate fully vaccinated people with Pfizer’s shot. The Wall Street Journal cites “dozens of recipients” as telling them they have been vaccinated again, some of whom reported developing no antibodies after their Sinopharm immunisation.

Despite overwhelming data on the efficacy of Sinopharm and Sinovac vaccines in countries such as Seychelles, UAE and Bahrain, Singapore is still paving the way for the availability of Chinese-made vaccines here to encourage more vaccination.

Allowing Sinovac and Sinopharm shots in Singapore without rigid testing is a step back against COVID efforts.


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新加坡7人“换妻”迷奸案细节公布!妻子被下药,全程录像直播...

Nov 03, 2022 | 🚀 Fathership AI

几名新加坡男子,在网上论坛认识后,沉浸在性幻想中无法自拔。

为了满足他们心中变态的好奇心,他们开始筹划换妻,并下药迷倒自己的妻子,让其他男子强奸自己的妻子!

昨天(10月31日),这起轰动新加坡一时的罪案在新加坡法庭进行了审理,涉案的七人中,有四人认罪,其中一人当场被判刑。

因为情况太过恶劣,为了保护受害人法院并未透漏她们的任何资料。被告人的名字也全部用字母代替。

回顾这起案件,这些男子的行径着实震碎了正常人的三观……

新加坡这名男子迷倒妻子 邀请其他人强奸并直播录像!

新加坡本体媒体《8视界新闻网》报道,法庭文件透露这起案件的主犯,是一名化名为J的新加坡男子。

J今年52岁,有着一份正当的工作,犯案时是一名业务拓展经理。这些年他和妻子一共生下了三个孩子,一家人原本很和谐地生活在一起。

不过在平静的生活下,J内心里涌动着一些邪恶的想法。

终于,在2010年,他在一个网络论坛上遇到了很多和自己臭味相投的人。在这个虚拟的平台,J肆无忌惮表露出自己的变态性癖,并发表了想玩换妻游戏的言论。

在这里,他们一起分享了很多有关“换妻”的想法。

聊着聊着,有一天他再也忍不住自己内心的想法,问自己妻子是否愿意接受3p。不出所料的,J的妻子拒绝了这个“提议”。

不过,这并没有阻止J付诸行动。

在一开始,包括J在内的一些人纷纷在家中安装网络摄像头。之后,他们会挑选时间告知网友相关的账号和密码,让他们自行观看自己和妻子的性爱视频。

经过一段时间后,J还是不满足。

于是,在某一天他下药迷晕了自己的妻子,然后邀请其他网友来家中与其发生关系!

随着事态的发展,J越来越沉迷其中……2013年,趁着妻子身体不适的时候,J还偷偷换了药物,再次邀请朋友来家中迷奸妻子。

这次,J竟然还打开了网络直播!

沉迷于“换妻游戏”,J不仅仅是让别人和自己妻子发生关系,同时他也跟其中一名网友K“商量好了”,趁着K迷晕自己妻子的工夫和她发生了性关系。

在某种程度上,K的行为更加恶劣,他甚至自己充当了摄像师的角色,拍下了J和自己妻子发生关系时的整段性爱视频……

渐渐的,J的妻子在不知情的情况下跟多人发生了性行为,相关视频还被上传到网络。

在当时,引起了相当多人的关注。

换妻行为曝光报警 更多人牵涉其中受重罚

J本以为这件事可以一直继续下去,不料在今年,他的妻子无意中看见丈夫手机在播放视频。

在好奇心的驱使下,她看到视频内容,这才恍然发现:

在过去的几年里,丈夫在暗地里进行了多次换妻活动,而自己在不知情的状态下被多次迷晕,在和他人强行强行发生关系后还被拍照记录……

拿着证据,J的妻子当面质问K,而K也承认自己曾经和昏迷的她有过性行为,并将自己妻子迷晕交给J的事实。

在得知真相后,J的妻子立即选择报警。随着案件的调查,调查人员惊讶地发现,还有更多人参与其中。

其中,有一名参加了J“举办的”换妻活动的L,也对自己的妻子如法炮制。

在一次在作案时,L的妻子尽管被下药后蒙住眼睛,在中途清醒了过来。

但L居然并未因此感到害怕而终止犯罪活动,而是要求自己一名同事P直接强行跟自己妻子发生关系,幸而L的妻子及时挣脱逃离,才免遭摧残。

之后,P在一封信中交代了全部经过,并表示自己不知道受害人并不知情才犯下罪案。

但法律并不会因为他的解释而对他开恩,最总P被判处三年监禁。他是涉案七名男子中,第一个被判刑的男子。

还有四人也已认罪,等待下一轮审讯。相信在严明的法律下,他们肯定无法逃脱坐牢。

不过,涉案情节严重的K在落网后,一再向警方和法官说自己有心理疾病,并要求医生为其检测,意图逃脱刑罚。

新加坡心理卫生院诊断后,确认了K患有偷窥症。但在审理中法官认为K对自己的非法行为是知情的,依旧是犯罪行为。

K对法院的说法表示不服,并要求开庭申辩。

但K的犯罪事实已被揭露,并且为自己的行为供认不讳,加上此案件牵连甚广,性质过于恶劣,估计也是难逃法律制裁。


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